姓名：曹新

職稱(chēng)：副研究員

教研室/研究室：科研中心

電子郵箱：caoxin@cdutcm.edu.cn

教育經(jīng)歷：

2013/4–2017/3東邦大學(xué)醫(yī)學(xué)部博士

2010/9–2013/6南京中醫(yī)藥大學(xué)第二臨床醫(yī)學(xué)院碩士2005/9–2010/6南京中醫(yī)藥大學(xué)基礎(chǔ)醫(yī)學(xué)院

工作履歷：

2017/4–2018/8東邦大學(xué)藥學(xué)院博士后

研究方向：針灸作用于心血管系統(tǒng)的效應(yīng)規(guī)律及其機(jī)制

主講課程：實(shí)驗(yàn)針灸學(xué)

科研教學(xué)成果：

承擔(dān)課題：

先后承擔(dān)日本和中國(guó)國(guó)家級(jí)課題2項(xiàng)，省級(jí)課題1項(xiàng)，校級(jí)課題2項(xiàng)

1.國(guó)家自然科學(xué)青年科學(xué)基金項(xiàng)目，81904306，鹽皮質(zhì)激素受體泛素化修飾介導(dǎo)電針延緩高血壓大鼠心臟電重構(gòu)機(jī)制，2020/01-2022/12, 21萬(wàn)，在研，主持

2.四川省科技計(jì)劃項(xiàng)目. 2020YFH0115，針刺對(duì)高血壓相關(guān)性心律失常的效應(yīng)特征及機(jī)制研究，2020/01-2023/12，50萬(wàn)元，在研，參與

3.平成29年度日本學(xué)術(shù)振興會(huì)科學(xué)研究費(fèi)助成事業(yè)(2017年日本學(xué)術(shù)振興會(huì)科學(xué)研究補(bǔ)助金) ，434，容量負(fù)荷から拡張不全への移行過(guò)程、増悪因子および治療標(biāo)的分子の解析(容量負(fù)荷導(dǎo)致舒張性心力衰竭的轉(zhuǎn)變過(guò)程,加重因素和治療靶向分子的探討) ，2017/10-2018/08；2860000 日円 (170000元)，結(jié)題，主持

4.東邦大學(xué)醫(yī)學(xué)院2016年項(xiàng)目基金，2830，心臟傳導(dǎo)系統(tǒng)和普通心肌的cAMP信號(hào)傳導(dǎo)差異的機(jī)制研究，2016/09-2017/03；340000 日円 (20000元)，已結(jié)題，主持

5.東邦大學(xué)醫(yī)學(xué)院2015年項(xiàng)目基金，2720，N型Ca2+離子通道阻滯劑治療冠心病心絞痛的療效和機(jī)制探討，2015/09-2016/03，450000 日円 (27000元)，已結(jié)題，主持

發(fā)表論文：

1. Cao X, Nagasawa Y, Zhang C, Zhang H, Aimoto M, Takahara A：  Acehytisine suppresses atrial fibrillation in rats with dilated atria caused by chronic volume overload.  Journal of Pharmacological Sciences. 2020, 142: 34 -40

2. Cao X, Nagasawa Y, Zhang C, Zhang H, Aimoto M, Takahara A. Electropharmacological profile of an atrial-selective sodium channel blocker acehytisine assessed in the isoflurane-anesthetized guinea-pig model.  Journal of Pharmacological Sciences. 2019, 141:153 -159.

3. Cao X, Aimoto M, Fukumoto M, Nagasawa Y, Tanaka H, Takahara A. Influence of chronic volume overload-induced atrial remodeling on electrophysiological responses to cholinergic receptor stimulation in the isolated rat atria. Journal of Pharmacological Sciences. 2018, 136: 73-78.

4. Cao X, Wada T, Nakamura Y, Matsukura S, Izumi-Nakaseko H, Ando K, Naito A, Sugiyama A. Sensitivity and reliability of halothane-anesthetized microminipigs to assess risk for drug-induced long QT syndrome. Basic & clinical pharmacology & toxicology. 2017. 121(6): 465-470.

5. Cao X, Nakamura Y, Wada T, Izumi-Nakaseko H, Ando K, Sugiyama A. L/N-type Ca2+ channels blocker cilnidipine ameliorated the repolarization abnormality in a chronic hemodialysis patient. Heart and Vessels. 2017, 32: 105-108

6. Cao X, Nakamura Y, Wada T, Izumi-Nakaseko H, Ando K, Sugiyama A. Electropharmacological effects of amantadine on cardiovascular system assessed with J-Tpeak and Tpeak-Tend analysis in the halothane-anesthetized beagle dogs. The Journal of Toxicological Sciences. 2016. 41: 439-447

7. Cao X, Nakamura Y, Aoki T, Wada T, Izumi-Nakaseko H, Ando K, Sakata R, Sugiyama A. Coronary artery vasospasms in a microminipig occurred after placing an ameroid constrictor. The Journal of Veterinary Medical Science. 2016, 78: 1213-1216,

8. Cao X, Nakamura Y, Takeshi Wada, Takuya Kishie, Azjargal Enkhsaikhan, Izumi-Nakaseko H, Ando K, Zhu BM, Xu B, Sugiyama A. Assessment of anti-anginal effect of tetramethylpyrazine using the vasopressin-induced angina model of rats. Bulletins of the Pharmaceutical Society of Japan. 2016, 39: 1370-1373.

9. Cao X, Nakamura Y, Wada T, Izumi-Nakaseko H, Ando K, Zhu B, Xu B, Takahara A, Saitoh M, Sugiyama A. Comparison of anti-anginal effect of cilnidipine with those of nicardipine and nifedipine in the vasopressin-induced angina model of rats. Heart and vessels. 2016, 31: 2045-2052.

10.Cao X, Lu S, Ohara H, Nakamura Y, Zhu BM, Xu B, Sugiyama A. Beneficial and adverse effects of electro-acupuncture assessed in the canine chronic atrio-ventricular block model having severe hypertension and chronic heart failure. Acupunct Electrother Res. 2015, 40: 87-99.