韓麗
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1、個(gè)人簡(jiǎn)介
韓麗，博士、教授、博士研究生導(dǎo)師；科技部國(guó)家科技專(zhuān)家?guī)鞂?zhuān)家，國(guó)家自然科學(xué)基金委同行評(píng)議專(zhuān)家，中國(guó)博士后科學(xué)基金評(píng)審專(zhuān)家，世界中醫(yī)藥聯(lián)合會(huì)中藥新型給藥系統(tǒng)專(zhuān)業(yè)委員會(huì)理事，世界中醫(yī)藥聯(lián)合會(huì)中藥飲片質(zhì)量專(zhuān)業(yè)委員會(huì)理事，四川省科技計(jì)劃項(xiàng)目評(píng)審專(zhuān)家，四川省高校師資培訓(xùn)中心進(jìn)修學(xué)者（醫(yī)藥類(lèi)）指導(dǎo)教師，四川省中醫(yī)藥管理局學(xué)術(shù)技術(shù)帶頭人。
作為課題負(fù)責(zé)人，承擔(dān)了科技部“十五”公關(guān)、國(guó)家新藥創(chuàng)制“十一五” 、“十二五” 重大專(zhuān)項(xiàng)、國(guó)家自然科學(xué)基金面上項(xiàng)目等7項(xiàng)國(guó)家級(jí)課題；作為主研，參與了國(guó)家 “九五” 攻關(guān)項(xiàng)目、國(guó)家 “863” 項(xiàng)目、藥典委員會(huì)、四川省科技廳等多項(xiàng)科研課題的研究工作；負(fù)責(zé)并參與多個(gè)中藥新藥的開(kāi)發(fā)，已有二十余個(gè)新藥上市生產(chǎn)。獲得四川省科技進(jìn)步三等獎(jiǎng)2項(xiàng)、江西省科技進(jìn)步二等獎(jiǎng)1項(xiàng)。作為主編出版教材及專(zhuān)著8部，副主編10部。發(fā)表文章270余篇。以第一發(fā)明人申請(qǐng)并獲得專(zhuān)利授權(quán)8項(xiàng)，其中轉(zhuǎn)讓2項(xiàng)。主要研究方向：中藥制劑新技術(shù)、新劑型研究。
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二、代表性成果
?期刊論文：
1. Jin Xie, Shimin Tian, Jun Liu, Shengjie Huang, Ming Yang, Xiangbo Yang, Runchun Xu, Junzhi Lin, Li Han*. Ding-kun Zhang. Combination therapy with indigo and indirubin for ulcerative colitis via reinforcing intestinal barrier function. Oxidative Medicine and Cellular Longevity. 2023;2894695
2. 黃勝杰，蘇娟，葛春麗，謝錦，郭治平，楊明，伍振峰，張定堃*，韓麗*. 基于粉體表面改性的青黛干混懸劑制備與評(píng)價(jià)，藥學(xué)學(xué)報(bào)，2023.2
3. Jun Liu, Jin Xie, Junzhi Lin, Xingliang Xie, Sanhu Fan, Xue Han, Ding-kun Zhang*, Li Han*. The material basis of astringency and the deastringent effect of polysaccharides: A revie. Food Chemistry. (2022) 134946
4. Xuan Deng, Haozhou Huang, Shengjie Huang, Ming Yang, Jing Wu, Zhimin Ci, Yanan He, Zhenfeng Wu, Li Han* and Dingkun Zhang*. Insight into the incredible effects of microwave heating: Driving changes in the structure, properties and functions of macromolecular nutrients in novel food. Frontiers in Nutrition. 2022.941527
5. Jiao Song, Wei Liao, Xuan Deng, Dingkun Zhang, Junzhi Lin, Runchun Xu*,Li Han* Analysis of the pharmacodynamic difference between Xiaojin Pills taken with Chinese Baijiu and water based on serum pharmacochemistry and pharmacokinetics. Journal of Ethnopharmacology. (2023) 115723
6. Shengjie Huang, Haozhou Huang, Jin Xie, Fang Wang, Sanhu Fan, Ming Yang, Chuan Zheng, Li Han*, Dingkun Zhang*. The latest research progress on the prevention of storage pests by natural products: Species, mechanisms, and sources of inspiration. Arabian Journal of Chemistry. 2022.104189
7. 譚慶芻，黃浩洲，林俊芝，仇敏，李莞，譚鵬，樊三虎，韓麗*，張定堃*. 余甘子藥材表面白霜的化學(xué)成分及“析霜”科學(xué)內(nèi)涵初探.中草藥，2022,53(11):3487-3495
8. Ji Yu, Jin Xie, Huijuan Xie, Qi Hu, Zhenfeng Wu, Xinfu Cai, Zhiping Guo, Junzhi Lin, Li Han* and Dingkun Zhang*. Strategies for Taste Masking of Orodispersible Dosage Forms: Time,Concentration, and Perception. Molecular pharmaceutics. 2022,9（3007）
9. Jin Xie; Shimin Tian; Jun Liu; Ruiyi Cao; Pengfei Yue; Xinfu Cai; Qiang Shang; Ming Yang; Li Han*. Ding-Kun Zhang*.Dual role of the nasal microbiota in neurological diseases—An unignorable risk factor or a potential therapy carrier. pharmarchological research.2022, 106189
10. Haozhou Huang; Peng Tan; Mengqi Li; Qinchu Tan; Jihai Gao; Xiaoming Bao; Sanhu Fan; Taigang Mo; Wanmin Mao; Feng Lin; Li Han*; Dingkun Zhang*; Junzhi Lin*. Quality analysis combined with mass spectrometry imaging reveal the difference between wild and cultivated Phyllanthus emblica Linn.: From chemical composition to molecular mechanism. Arabian Journal of Chemistry. 2022.103790
11. Qian-hui Zhang, Hao-zhou Huang, Min Qiu, Zhen-feng Wu, Zhan-chang Xin,Xin-fu Cai, Qiang Shang, Jun-zhi Lin, Ding-kun Zhang* and Li Han*. Traditional Uses, Pharmacological Effects, and Molecular Mechanisms of Licorice in Potential Therapy of COVID-19. Frontiers in Pharmacology. 2021.719758
12. Jiao Song, Bi Feng, Dingkun Zhang, Min Qiu, Fei Ran, Bo Cao, Hong Xu, Junzhi Lin*, Runchun Xu*, Li Han*. Comparative study on the pharmacodynamic difference of oral administration of Xiaojin Pills accompanied with Chinese Baijiu and water. Journal of Ethnopharmacology. 2021, 278:114284
13. 黃浩洲，冉飛，林俊芝，李夢(mèng)琪，鄒文銓?zhuān)?，楊明，許潤(rùn)春，韓麗*，張定堃*.多酚類(lèi)液體制劑精細(xì)制造關(guān)鍵：多元沉淀形成原理與穩(wěn)態(tài)重構(gòu).藥學(xué)學(xué)報(bào)，2020,55(1):45-53
獲獎(jiǎng)：
基于粉體改性原理的中藥分散片成型速崩關(guān)鍵技術(shù)創(chuàng)建及產(chǎn)業(yè)化應(yīng)用，2019年獲四川省科技進(jìn)步三等獎(jiǎng)，排名第一，項(xiàng)目主持人