羅開(kāi)沛
一、個(gè)人簡(jiǎn)介
羅開(kāi)沛，特聘副研究員，碩士生導(dǎo)師（破格），中藥資源與鑒定碩士研究生第一黨支部書(shū)記。中國(guó)藥科大學(xué)藥劑學(xué)博士，成都中醫(yī)藥大學(xué)中藥學(xué)博士后。入選中華中醫(yī)藥學(xué)會(huì)青年人才托舉工程，成都中醫(yī)藥大學(xué)杏林學(xué)者“1313”高層次人才。
主要從事中藥納米遞釋系統(tǒng)的研究。主持國(guó)家自然科學(xué)基金青年基金、中國(guó)博士后科學(xué)基金面上項(xiàng)目、四川省自然科學(xué)基金面上項(xiàng)目等科研項(xiàng)目7項(xiàng)。在國(guó)內(nèi)外期刊發(fā)表學(xué)術(shù)論文50余篇，包括Small、Chemical Engineering Journal、Acta Biomaterialia、ACS Applied Materials & Interfaces等國(guó)際著名雜志，其中高被引論文1篇，封面論文1篇。為Journal of Nanobiotechnology、ACS Applied Materials & Interfaces等期刊審稿人。協(xié)助指導(dǎo)研究生獲得國(guó)家獎(jiǎng)學(xué)金、省級(jí)/校級(jí)優(yōu)秀畢業(yè)生等榮譽(yù)。指導(dǎo)本科生榮獲“全國(guó)大學(xué)生藥苑論壇”創(chuàng)新成果一等獎(jiǎng)和優(yōu)秀論文獎(jiǎng)，立項(xiàng)大學(xué)生創(chuàng)新創(chuàng)業(yè)課題3項(xiàng)。獲優(yōu)秀學(xué)士論文指導(dǎo)教師。
聯(lián)系方式：luokaipei@cdutcm.edu.cn
二、代表性成果
（一）科研項(xiàng)目
1. 國(guó)家自然科學(xué)基金青年基金，82204633，2023.01-2025.12，30萬(wàn)，主持
2. 中國(guó)博士后科學(xué)基金面上項(xiàng)目，2021M700550，2021.12-2024.08，8萬(wàn)，主持
3. 四川省自然科學(xué)基金面上項(xiàng)目，2022NSFSC0634，2022.01-2023.12，20萬(wàn)，主持
4. 四川省科教聯(lián)合基金面上項(xiàng)目，2024NSFSC2112，2024.11-2026.10，20萬(wàn)，主持
5. 成都中醫(yī)藥大學(xué)“杏林學(xué)者”提升計(jì)劃，BSH2021024，2021.12-2024.08，12萬(wàn)，主持
6. 成都中醫(yī)藥大學(xué)“杏林學(xué)者”提升計(jì)劃，QJRC2024021，2024.12-2026.11，18萬(wàn)，主持
7. 中華中醫(yī)藥學(xué)會(huì)（2024-2026年度）青年人才托舉工程，2024-QNRC2-B28，主持
（二）學(xué)術(shù)論文
1. Kaipei Luo*, Lu Yang, Chunmei Yan, Yuxin Zhao, Qiuxia Li, Xing Liu, Long Xie, Qiang Sun, Xiaofang Li*. A dual-targeting liposome enhances triple-negative breast cancer chemoimmunotherapy through inducing immunogenic cell death and inhibiting STAT3 activation. Small, 2023, 19: 2302834.（IF: 13.3，中科院一區(qū)，封面論文）
2. Qiuxia Li, Xing Liu, Chunmei Yan, Bolin Zhao, Yuxin Zhao, Lu Yang, Mingyi Shi, Hua Yu*, Xiaofang Li*, Kaipei Luo*. Polysaccharide-based stimulus-responsive nanomedicines for combination cancer immunotherapy. Small, 2023, 19: 2206211.（IF: 13.3，中科院一區(qū)）
3. Kaipei Luo, Yunfei Lian, Min Zhang, Hua Yu, Guangji Wang, Juan Li*. Charge convertible biomimetic micellar nanoparticles for enhanced melanoma-targeted therapy through tumor cells and tumor-associated macrophages dual chemotherapy with IDO immunotherapy. Chemical Engineering Journal, 2021, 412: 128659.（IF: 16.744，中科院一區(qū)）
4. Kaipei Luo, Yi Gao, Shaoping Yin, Yawen Yao, Hua Yu*, Guangji Wang, Juan Li*. Co-delivery of paclitaxel and STAT3 siRNA by multifunctional nanocomplexes for targeted treatment of metastatic breast cancer. Acta Biomaterialia, 2021, 134: 650-664.（IF: 10.633，中科院一區(qū)）
5. Chunmei Yan, Yuxin Zhao, Xiaolian Liu, Yingjie Jiang, Qiuxia Li, Lu Yang*, Xiaofang Li*, Kaipei Luo*. Self-delivery Nano-booster to Enhance Immunogenic Cell Death for Cancer Chemoimmunotherapy. ACS Applied Materials & Interfaces, 2024, 16: 33169-33181.（IF: 9.5，中科院二區(qū)）
6. Chunmei Yan, Qiuxia Li, Qiang Sun, Lu Yang, Xing Liu, Yuxin Zhao, Mingyi Shi, Xiaofang Li*, Kaipei Luo*. Promising nanomedicines of shikonin for cancer therapy. International Journal of Nanomedicine, 2023, 18: 1195-1218.（IF: 8.0，中科院二區(qū)，ESI高被引論文）
7. Kaipei Luo, Shaoping Yin, Ruixia Zhang, Hua Yu, Guangji Wang, Juan Li. Multifunctional composite nanoparticles based on hyaluronic acid-paclitaxel conjugates for enhanced cancer therapy. International Journal of Pharmaceutics, 2020, 589: 119870.（IF: 6.51，中科院二區(qū)）
8. Kaipei Luo, Feng Xu, Tianyi Yao, Jianping Zhu, Hua Yu, Guangji Wang, Juan Li*. TPGS and chondroitin sulfate dual-modified lipid-albumin nanosystem enhances the targeted therapy of chemotherapeutic agent against multidrug-resistant cancer. International Journal of Biological Macromolecules, 2021, 183: 1270-1282.（IF: 8.025，中科院一區(qū)）
9. Yingjie Jiang, Chunmei Yan, Minghao Li, Siying Chen, Zhimin Chen*, Lu Yang*, Kaipei Luo*. Delivery of natural products via polysaccharide-based nanocarriers for cancer therapy: A review on recent advances and future challenges. International Journal of Biological Macromolecules, 2024, 278: 135072.（IF: 7.7，中科院一區(qū)，本科生一作）
10. Lu Yang, Xianfeng Liu, Siyin Chen, Jiayi Sun, Yiwen Tao, liyuan Ma, Yong Zeng, Kaipei Luo*, Ruimin Tian*, Xianli Meng*. Scutellarin Ameliorates Mitochondrial Dysfunction and Apoptosis in OGD/R-Insulted HT22 Cells through Mitophagy Induction. Biomedicine & Pharmacotherapy, 2024, 179: 117340.（IF: 6.9，中科院二區(qū)）