張楊
一、個(gè)人簡(jiǎn)介
張楊，成都中醫(yī)藥大學(xué)中醫(yī)藥創(chuàng)新研究院副教授，長(zhǎng)期致力于生物信息學(xué)領(lǐng)域的研究工作，目前已成功開發(fā)了多個(gè)生物醫(yī)學(xué)相關(guān)數(shù)據(jù)庫、算法和分析平臺(tái)，為來自30多個(gè)國家和地區(qū)的科研人員提供了重要的服務(wù)和資源支持，其中部分工作對(duì)單細(xì)胞組學(xué)及RNA組學(xué)研究領(lǐng)域具有重要推動(dòng)作用，主要研究成果以第一作者或通訊作者的身份發(fā)表在《Nucleic Acids Research》、《Briefings in Bioinformatics》、《Bioinformatics》等生物信息學(xué)領(lǐng)域的頂級(jí)刊物上（IF高于15的論文2篇、IF高于10的論文4篇），目前已主持多項(xiàng)國家級(jí)和省部級(jí)科學(xué)基金項(xiàng)目（主持國家自然科學(xué)基金1項(xiàng)、省部級(jí)自然科學(xué)基金2項(xiàng)、生物制藥企業(yè)橫向基金1項(xiàng)）。郵箱：yangzhang@cdutcm.edu.cn。實(shí)驗(yàn)室網(wǎng)站：http://www.zhangy-lab.cn/。
二、主要研究方向
（1） 中醫(yī)藥相關(guān)數(shù)據(jù)資源整合及數(shù)據(jù)庫開發(fā)；
（2） AI輔助的藥物設(shè)計(jì)研究；
（3） 單細(xì)胞測(cè)序數(shù)據(jù)挖掘及算法開發(fā)。
三、近三年科研成果
已發(fā)表或接受的第一作者及通訊作者論文：
2023年：
[1] Yang Zhang, Caiqi Liu, Mujiexin Liu, Tianyuan Liu, Hao Lin, Chengbing Huang, Lin Ning. Attention is all you need: Utilizing attention in AI-enabled drug discovery. Briefings in Bioinformatics, 2023.（accepted）（2023 IF: 9.5）.
[2] Yang Zhang, Xianrun Pan, Tianyu Shi, Zhifeng Gu, Zhaochang Yang, Minghao Liu, Yi Xu, Yu Yang, Liping Ren, Xiaoming Song, Hao Lin, Kejun Deng. P450Rdb: a manually curated database of reactions catalyzed by cytochrome P450 enzymes. Journal of Advanced Research. （2023 IF: 10.7）.
[3] Liping Ren, Lin Ning, Yu Yang, Ting Yang, Xinyu Li, Shanshan Tan, Peixin Ge, Shun Li, Nanchao Luo, Pei Tao, Yang Zhang. MetaboliteCOVID: A manually curated database of metabolite markers for COVID-19. Computers in Biology and Medicine, 167, 107661. （2023 IF: 7.7）.
[4] Yu-Fei Zhang, Yu-Hao Wang, Zhi-Feng Gu, Xian-Run Pan, Jian Li, Hui Ding, Yang Zhang, Ke-Jun Deng. Bitter-RF: a random forest machine model for recognizing bitter peptides. Frontiers in Medicine,2023,10, 1052923. （2023 IF: 3.9，全球高被引論文）.
2022年：
[5] Hao Lv, Yang Zhang, Jia-Shu Wang, Shi-Shi Yuan, Zi-Jie Sun, Fu-Ying Dao, Zheng-Xing Guan, Hao Lin*, Ke-Jun Deng*, iRice-MS: An integrated XGBoost model for detecting multitype post-translational modification sites in rice, Briefings in Bioinformatics, 2022, 23(1): bbab486. （2022 IF: 11.622）.
[6] Liping Ren, Yi Xu, Lin Ning, Xianrun Pan, Yuchen Li, Qi Zhao, Bo Pang, Jian Huang*, Kejun Deng*, Yang Zhang. TCM2COVID: A resource of anti‐COVID‐19 traditional Chinese medicine with effects and mechanisms. iMeta, 2022, 1(4): e42（國產(chǎn)期刊）.
[7] 任麗萍, 寧琳, 謝雷, 張楊. 腫瘤免疫微環(huán)境中免疫細(xì)胞間通訊景觀探究.電子科技大學(xué)學(xué)報(bào), 2022,51(2):177-183. （EI）.
2021年：
[8] Yang Zhang, Tianyuan Liu, Xuesong Hu, Mei Wang, Jing Wang, Bohao Zou, Puwen Tan, Tianyu Cui, Yiying Dou, Lin Nin, Yan huang, Shuan Rao, Dong Wang, Xiaoyang Zhao. CellCall: Integrating paired ligand-receptor and transcription factor activities for cell-cell communication. Nucleic Acids Research, 2021, 49(15): 8520-8534. （2021 IF: 19.16）.
[9] Yan Huang, Jing Wang, Yue Zhao, Huafeng Wang, Tianyuan Liu, Yuhe Li, Tianyu Cui, Weiyi Li, Yige Feng, Jiaxin Luo, Jiaqi Gong, Lin Ning, Yong Zhang*, Dong Wang*, Yang Zhang. cncRNAdb: a manually curated resource of experimentally supported RNAs with both protein-coding and noncoding function. Nucleic Acids Research, 2021, 49(D1): D65-D70. （2021 IF: 19.16）.
[10] Yang Zhang, Tianyuan Liu, Jing Wang, Bohao Zou, Le Li, Linhui Yao, Kechen Chen, Lin Ning, Bingyi Wu, Xiaoyang Zhao, Dong Wang. Cellinker: a platform of ligand-receptor interactions for intercellular communication analysis. Bioinformatics. 2021. 37(14): 2025-2032. （2021 IF: 6.931）.
[11] Hao Lv, Lei Shi, Joshua William Berkenpas, Fu-Ying Dao, Hasan Zulfiqar, Hui Ding, Yang Zhang, Liming Yang, Renzhi Cao. Application of artificial intelligence and machine learning technologies for SARS-CoV-2 drugs and vaccines. Briefings in Bioinformatics, 2021, 22(16): bbab320. （2021 IF: 13.994）.