劉娟
一．個(gè)人簡(jiǎn)介
劉娟，博士，博士后，副教授，碩士生導(dǎo)師，藥學(xué)院/現(xiàn)代中藥產(chǎn)業(yè)學(xué)院中藥藥理教研室專任教師。主要致力于中藥治療痛經(jīng)的物質(zhì)基礎(chǔ)及作用機(jī)制研究。主持國(guó)家自然科學(xué)基金青年項(xiàng)目1項(xiàng)，四川省科技廳項(xiàng)目3項(xiàng)，成都中醫(yī)藥大學(xué)杏林學(xué)者項(xiàng)目2項(xiàng)。共發(fā)表學(xué)術(shù)論文30余篇，參與出版專著5部，參編中藥藥理學(xué)教材3部，申請(qǐng)國(guó)家發(fā)明專利8項(xiàng)（授權(quán)4項(xiàng)），獲得四川省科技進(jìn)步獎(jiǎng)一等獎(jiǎng)1項(xiàng)?，F(xiàn)為世界中醫(yī)藥學(xué)會(huì)聯(lián)合會(huì)道地藥材多維評(píng)價(jià)專業(yè)委員會(huì)會(huì)員、四川省生理科學(xué)學(xué)會(huì)會(huì)員。
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二、代表性成果
（一）承擔(dān)項(xiàng)目
1.國(guó)家自然科學(xué)基金委員會(huì)，青年科學(xué)基金項(xiàng)目，82104371，基于PTGFR-IP3/DAG-Ca2+通路研究莪術(shù)油倍半萜治療痛經(jīng)的物質(zhì)基礎(chǔ)及作用機(jī)制，2022/01-2024/12，30萬(wàn)，已結(jié)題，主持
2. 四川省科學(xué)技術(shù)廳,自然科學(xué)基金面上項(xiàng)目, 2025ZNSFSC0569, 基于MAPK信號(hào)通路研究莪術(shù)倍半萜治療原發(fā)性痛經(jīng)的靶點(diǎn)及分子機(jī)制, 2025-01至2026-12, 20萬(wàn)元, 在研, 主持
3. 四川省科學(xué)技術(shù)廳,自然科學(xué)基金青年基金項(xiàng)目, 2022NSFSC1332, 莪術(shù)治療痛經(jīng)新穎倍半萜的發(fā)現(xiàn)及其對(duì)PTGFR受體通路的影響, 2022-01至2023-12, 10萬(wàn)元,已結(jié)題, 主持
4. 四川省科技廳, 科技創(chuàng)新（苗子工程）培育項(xiàng)目, 2019046, 一種緩解痛經(jīng)癥狀的川芎臍貼片開(kāi)發(fā)研究, 2019-07至2020-07, 2萬(wàn)元,已結(jié)題, 主持
5. 成都中醫(yī)藥大學(xué), “杏林學(xué)者”學(xué)科人才科研提升計(jì)劃青基人才專項(xiàng), QJRC2022020, 莪術(shù)治療痛經(jīng)新穎倍半萜的發(fā)現(xiàn)及其對(duì)PTGFR受體通路的影響, 2022-10至2024-10, 18萬(wàn)元, 在研, 主持
6. 成都中醫(yī)藥大學(xué), “杏林學(xué)者”學(xué)科人才科研提升計(jì)劃, BSH2019028, 川芎治療痛經(jīng)的新穎成分的研究與發(fā)現(xiàn), 2019-12至2022-12, 9萬(wàn)元, 結(jié)題, 主持
（二）發(fā)表論文
1. Juan Liu#, Ming-Ming Qiao#, Cheng Peng *,Hong-Zhen Shu, Chun-Wang Meng, Fei Liu* and Liang Xiong*; Curcumanes E and F, two rare sesquiterpenoids with a dicyclo[3.3.1]nonane moiety, from Curcuma longa and their vasorelaxant activities, Frontiers in Chemistry, 2022, 10: 995950.
2. Juan Liu#, Rui Feng#, Ou Dai *, Hong Ni, Lu-Si Liu, Hong-Zhen Shu, Yan Lu, Cheng Peng *, Liang Xiong * ; Isoindolines and phthalides from the rhizomes of Ligusticum chuanxiong and their relaxant effects on the uterine smooth muscle, Phytochemistry, 2022，198,113159.
3. Rui Feng#, Juan Liu#, Li Guo*, Hong-Zhen Shu, Qin-Mei Zhou, Li Liu, Cheng Peng *, Liang Xiong *. A pair of new enantiomeric hybrid phthalide–adenines with a rare 5-oxa-1-azaspiro[3,4]octane moiety and two pairs of new enantiomeric hybrid paraethyl phenol–adenines from Ligusticum chuanxiong, Arabian Journal of Chemistry, 2023, 16, 104696.
4. Lei Li# , Juan Liu#, Xinrui Li, Yuqin Guo , Yunqiu Fan , Hongzhen Shu , Guangxu Wu, Cheng Peng* , Liang Xiong*; Sesquiterpenoids from the Florets of Carthamus tinctorius (Safflower) and Their Anti-Atherosclerotic Activity, Nutrients, 2022, 14, 5348.
5. Hong Ni#; Juan Liu#; Ou Dai; Rui Feng; Fei Liu; Xiao-Yu Cao; Cheng Peng*; Liang Xiong*; Chemical composition and uterine smooth muscle relaxant activity of essential oils from 10 kinds of blood-activating and stasis-resolving Chinese medicinal herbs, Journal of Ethnopharmacology, 2021, 269: 113713.
6. Xin-Rui Li#; Juan Liu#; Cheng Peng; Qin-Mei Zhou; Fei Liu; Li Guo* ; Xiong Liang*, Polyacetylene glucosides from the florets of Carthamus tinctorius and their anti-inflammatory activity, Phytochemistry, 2021, 187: 112770.
7. Mei-Ji Sun, Rui Zhao, Min Wen, Chun-Wang Meng, Hai-guo Su, Fu-Xin Mi, Cheng Peng, Juan Liu*, Liang Xiong*，Two new phenolic glycosides from Cyathula officinalis and their relaxant effects on uterine smooth muscle, Phytochemistry Letters, 2025, 66: 100-104.
8. Rui Zhao, Cheng Peng*, Lei Li, Xin-Rui Li, Chun-Wang Meng, Juan Liu*, Liang Xiong*，A new arborinane-type triterpenoid glycoside and three known megastigmanes from the roots of Cyathula officinalis K.C.Kuan，Biochemical Systematics and Ecology, 2022, 104: 104489.
9. Juan Liu; Cheng Peng*; Qin-Mei Zhou; Li Guo; Zhao-Hua Liu; Liang Xiong*; Alkaloids and flavonoid glycosides from the aerial parts of Leonurus japonicus and their opposite effects on uterine smooth muscle, Phytochemistry, 2018, 145: 128-136.
10. Juan Liu; Cheng Peng*; Cheng-Jun He; Jian-Lin Liu; Ya-Cong He; Li Guo; Qin-Mei Zhou; Huai Yang; Liang Xiong*; New amino butenolides from the bulbs of Fritillaria unibracteata, Fitoterapia, 2014, 98: 53-58.
（三）獲獎(jiǎng)
1. 經(jīng)產(chǎn)良藥益母草的多維評(píng)價(jià)與開(kāi)發(fā)應(yīng)用，2017年度四川省科技進(jìn)步獎(jiǎng)，一等獎(jiǎng)