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中藥分析方向

蘇海國(guó)

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一、個(gè)人簡(jiǎn)介

2021年畢業(yè)于中國(guó)科學(xué)院昆明植物研究所,獲得藥物化學(xué)博士學(xué)位,同年到中山大學(xué)藥學(xué)院藥理系進(jìn)行博士后研究,現(xiàn)任成都中醫(yī)藥大學(xué)特聘副研究員,碩士生導(dǎo)師,入選四川省優(yōu)秀青年人才項(xiàng)目。主要研究方向?yàn)樘烊划a(chǎn)物調(diào)控代謝穩(wěn)態(tài)在疾病中的應(yīng)用及機(jī)制,近年來(lái)對(duì)赤芝、樹(shù)舌靈芝、黃邊靈芝、反柄紫芝、田基黃等中藥的藥效物質(zhì)基礎(chǔ)進(jìn)行了系統(tǒng)研究,發(fā)現(xiàn)新化合物100余個(gè),探索了它們對(duì)于脂質(zhì)代謝和膽汁酸代謝的影響,在國(guó)內(nèi)外期刊發(fā)表論文20余篇,目前主持國(guó)家自然科學(xué)基金青年項(xiàng)目1項(xiàng)、四川省自然科學(xué)基金面上項(xiàng)目1項(xiàng)。擔(dān)任世中聯(lián)中藥分析專(zhuān)委會(huì)理事,廣東省藥理學(xué)會(huì)藥物代謝專(zhuān)業(yè)委員會(huì)委員,Chinese Herbal Medicines、Food & Medicine Homology等期刊青年編委,Chemical Communications等期刊常邀審稿人。


Email:suhaiguo@cdutcm.edu.cn


二、代表性成果(可含承擔(dān)項(xiàng)目、發(fā)表論文、論著、獲獎(jiǎng)等)

承擔(dān)課題

1. 國(guó)家自然科學(xué)基金青年項(xiàng)目,田基黃中PXR小分子激動(dòng)劑的發(fā)現(xiàn)及其抗膽汁淤積性肝損傷研究,2023.01?2025.12,30萬(wàn)元,主持

2. 成都中醫(yī)藥大學(xué),引進(jìn)人才科研啟動(dòng)經(jīng)費(fèi),2023.01?2025.12,25萬(wàn)元,主持

5代表性論文】

1.  Liu X.J. #; Su, H.G. #; Peng, X. R.; Bi, H.C.*; Qiu, M. H.*, An updated review of the genus Rhododendron since 2010: Traditional uses, phytochemistry, and pharmacology. Phytochemistry 2024, 217, 113899. (中科院2區(qū))

2.  Su, H.G.; Liang, H.F.; Hu, G.L.; Zhou, L., Peng, X. R.*; Bi, H.C.*; Qiu, M. H.*, Applanoids A?E as the first examples of C-15/C-20 Michael adducts in Ganoderma triterpenoids and their PXR agonistic activity. Chinese journal of Chemistry, 2022, 40(22), 2633-2641. Cover Story, 中科院2區(qū))

3.  Su, H.-G.#; Wang, Q. #; Zhou, L.; Peng, X.-R.*; Xiong, W.-Y.*; Qiu, M.-H.*, Functional triterpenoids from medicinal fungi Ganoderma applanatum: a continuous search for antiadipogenic agents. Bioorganic Chemistry, 2021,112, 104977.(中科院1區(qū))

4.  Peng X.-R.#; Su, H.-G.#; Wang, H.-R.; Hu, G.-L.; Hu, K.; Zhou, L.; Qiu, M.-H.*, Applanmerotic acids A and B, two meroterpenoid dimers with an unprecedented polycyclic skeleton from Ganoderma applanatum that inhibit formyl peptide receptor 2. Organic Chemistry Frontiers, 2021,8(13),3381-3389. (中科院1區(qū))

5. Su, H.-G.#; Wang, Q. #; Zhou, L.; Peng, X.-R.*; Xiong, W.-Y.*; Qiu, M.-H.*, Highly oxygenated lanostane triterpenoids from Ganoderma applanatum as a class of agents for inhibiting lipid accumulation in adipocytes. Bioorganic Chemistry 2020, 104, 104263. (中科院1區(qū))

6. Su, H.-G.; Peng, X.-R.; Shi, Q.-Q.; Huang, Y.-J.; Zhou, L.; Qiu, M.-H.*, Lanostane triterpenoids with anti-inflammatory activities from Ganoderma lucidum. Phytochemistry 2020, 173, 112256. (中科院2區(qū))

7. Su, H.-G.; Zhou, Q.-M.; Guo, L.; Huang, Y.-J.; Peng, C.; Xiong, L.*, Lanostane triterpenoids from Ganoderma luteomarginatum and their cytotoxicity against four human cancer cell lines. Phytochemistry 2018, 156, 89-95. (中科院2區(qū))

終審:藥學(xué)院總管理賬號(hào)
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