孔維軍
一、 個人簡介
2011年畢業(yè)于成都中醫(yī)藥大學(xué)，醫(yī)學(xué)博士。教授，博士研究生導(dǎo)師，博士后合作導(dǎo)師，首都醫(yī)科大學(xué)中醫(yī)藥學(xué)院引進人才。現(xiàn)任中國醫(yī)學(xué)科學(xué)院藥用植物研究所碩士研究生導(dǎo)師，河南大學(xué)、成都中醫(yī)藥大學(xué)和江西中醫(yī)藥大學(xué)碩士研究生兼職導(dǎo)師。中華中醫(yī)藥學(xué)會“青年托舉人才”、“協(xié)和新星”、中國醫(yī)學(xué)科學(xué)院“青年醫(yī)學(xué)人才”、藥植所“杰出青年人才”和“優(yōu)秀指導(dǎo)教師”獲得者。擔(dān)任中華中醫(yī)藥學(xué)會中成藥分會常務(wù)委員，中華中醫(yī)藥學(xué)會中藥化學(xué)分會第四屆委員會委員，中國藥學(xué)會第一屆臨床中藥學(xué)專業(yè)委員會委員。國家自然科學(xué)基金和北京市自然科學(xué)基金項目通訊評審專家，教育部學(xué)位與研究生教育學(xué)位論文評審專家。Journal of Pharmaceutical Analysis、Chinese Medicine、Journal of Analysis and Testing、Acta Materia Medica、Chinese Herbal Medicines、《分析實驗室》、《中國藥物警戒》、《中南藥學(xué)》等期刊青年編委；Pharmacological Research-Modern Chinese Medicine、Frontiers in Plant Science、Molecules期刊客座編輯（Guest Editor）。
研究方向為中藥質(zhì)量和安全性評價及臨床樣本痕量成分檢測新方法開發(fā)。先后主持國家自然科學(xué)基金面上項目（4項）、北京市自然科學(xué)基金面上項目（2項）等10余項。以第一/通訊作者在Comprehensive Reviews in Food Science and Food Safety、Trends in Food Science & Technology、Trends in Analytical Chemistry、Biosensors and Bioelectronics、Journal of Hazardous Materials、Analytical Chemistry、Food Chemistry等高水平SCI期刊發(fā)表論文90余篇。指導(dǎo)的研究生中多人獲得“國家獎學(xué)金”及“北京市優(yōu)秀畢業(yè)生”等稱號。
二、代表性成果
1、主持承擔(dān)科研項目
（1）國家自然科學(xué)基金面上項目：基于自然光驅(qū)動“敏化探針-MOFs納米酶”可穿戴PEC適配體傳感器的中藥材上多農(nóng)藥殘留現(xiàn)場無毒無損智能檢測研究（82274089），2023年1月—2026年12月，在研。
（2）國家自然科學(xué)基金面上項目：基于“復(fù)合納米探針-智能手機熒光讀取”微流層析適配體傳感器的中藥多農(nóng)藥殘留現(xiàn)場“掌上檢測”研究（81973474），2020年1月—2023年12月，在研。
（3）北京市自然科學(xué)基金面上項目：基于“重組抗體-金屬有機骨架”光電化學(xué)傳感器的中藥材上三嗪類農(nóng)藥“掌上檢測”研究（7232265），2023年1月—2025年12月，在研。
（4）國家自然科學(xué)基金面上項目：基于脫氧核酶和納米探針雙重信號放大的電致化學(xué)發(fā)光超敏傳感器現(xiàn)場檢測中藥真菌毒素研究（81673593），2017年1月—2020年12月，已結(jié)題。
（5）國家自然科學(xué)基金面上項目：基于“流式微球-適體芯片”的中藥真菌毒素現(xiàn)場高通量“掌上檢測”體系構(gòu)建（81473346），2015年1月—2018年12月，已結(jié)題。
（6）北京市自然科學(xué)基金面上項目：基于“基因工程抗體-量子點”微陣列傳感器的中藥材中酰胺類農(nóng)藥高通量可視化檢測研究（7192130），2019年1月—2021年12月。
2、發(fā)表論文
以第一/通訊作者在Trends in Food Science & Technology、Comprehensive Reviews in Food Science and Food Safety、Journal of Hazardous Materials、Trends in Analytical Chemistry、Biosensors & Bioelectronics、Food Chemistry、Microbiology Spectrum、Chemosphere、Analytical Chemistry、Food Research International、Ecotoxicology and Environmental Safety等國際刊物發(fā)表論文90余篇。部分論文如下：
2023年：
1. Yujiao Hou, Nan Long, Qingbin Xu, Ying Li, Pengyue Song, Minghan Yang, Jiabo Wang, Lidong Zhou, Ping Sheng, Weijun Kong*. Development of a Nafion-MWCNTs and in-situ generated Au nanopopcorns dual-amplification electrochemical aptasensor for ultrasensitive detection of OTA. Food Chemistry, 2023, 403: 134375.
2. Xiaofang Liao, Ying Li, Nan Long, Qingbin Xu, Peng Li, Jiabo Wang, Lidong Zhou, Weijun Kong*. Multi-mycotoxin detection and human exposure risk assessment in medicinal foods. Food Research International, 2023, 164: 112456.
3. Yujiao Hou, Qingbin Xu, Ying Li, Nan Long, Peng Li, Jiabo Wang, Lidong Zhou, Ping Sheng, Weijun Kong*. Ultrasensitive electrochemical aptasensor with Nafion-stabilized f-MWCNTs as signal enhancers for OTA detection. Bioelectrochemistry, 2023, 151: 108399.
2022年：
1. Yujiao Hou, Boyu Jia, Ping Sheng, Xiaofang Liao, Linchun Shi, Ling Fang, Lidong Zhou, Weijun Kong*. Aptasensors for mycotoxins in foods: Recent advances and future trends. Comprehensive Reviews in Food Science and Food Safety, 2022, 21: 2032-2073.
2. Xin Zhang, Xiaofang Liao, Yujiao Hou, Boyu Jia, Lizhu Fu, Mingxuan Jia, Lidong Zhou, Jinghua Lu, Weijun Kong*. Recent advances in synthesis and modification of carbon dots for optical sensing of pesticides. Journal of Hazardous Materials, 2022, 422, 126881.
3. Nan Long#, Jinxin Liu#, Jiali Liu, Ying Li, Yujiao Hou, Xiaofang Liao, Lidong Zhou, Linchun Shi*, Weijun Kong*. Single-Molecule Real-Time Sequencing to Explore the Mycobiome Diversity in Malt. Microbiology Spectrum, 2022, 10(5): 00511-22.
4. Ling Fang, Nan Long, Ying Li, Xiaofang Liao, Linchun Shi, Haiping Zhao, Lidong Zhou, Weijun Kong*. Transfer behavior of pesticides from honeysuckle into tea infusions: Establishment of an empirical model for transfer rate prediction. Ecotoxicology and Environmental Safety, 2022, 234: 113377.
5. Mingxuan Jia, Boyu Jia, Xiaofang Liao, Linchun Shi, Zheng Zhang, Miao Liu, Lidong Zhou, Donghui Li, Weijun Kong*. A CdSe@CdS quantum dots based electrochemiluminescence aptasensor for sensitive detection of ochratoxin A. Chemosphere, 2022, 287, 131994.
6. Yujiao Hou, Nan Long, Boyu Jia, Xiaofang Liao, Minghan Yang, Lizhu Fu, Lidong Zhou, Ping Sheng*, Weijun Kong*. Development of a label-free electrochemical aptasensor for ultrasensitive detection of ochratoxin A. Food Control, 2022, 135: 108833.
7. Xin Zhang, Lizhu Fu, Yujiao Hou, Nan Long, Guangqiang Zhu, Xiaofang Liao, Lidong Zhou, Jinghua Lu, Weijun Kong*. A nitrogen-doped carbon dots based fluorescent nanosensor for sensitive assay of Fe3+ ions in Dioscorea opposita Thunb. Industrial Crops & Products, 2022, 177: 114439.
8. Qing Zhang, Linzhi Kang, Pengfei Yue, Linchun Shi, Meng Wang, Lidong Zhou, Haiping Zhao*, Weijun Kong*. Development of a graphene oxide nanosheet and double-stranded DNA structure based fluorescent “signal off” aptasensor for ochratoxin A detection in malt. Food Chemistry: X, 2022, 14: 100308.
9. Lizhu Fu, Yujiao Hou, Haipeng Guo, Chang Liu, Ying Li, Boyu Jia, Lidong Zhou, Weijun Kong*. Gold nanoparticles and nitrogen-doped carbon dots based fluorescent nanosensor for ultrasensitive detection of thiram in hawthorn. Microchemical Journal, 2022, 176: 107253.
2021年：
1. Ling Fang, Mingxuan Jia, Haiping Zhao, Linzhi Kang, Linchun Shi, Lidong Zhou, Weijun Kong*. Molecularly imprinted polymer-based optical sensors for pesticides in foods: Recent advances and future trends. Trends in Food Science & Technology, 2021, 116, 387-404.
2. Qing Zhang, Ling Fang, Boyu Jia, Nan Long, Linchun Shi, Lidong Zhou, Haiping Zhao, Weijun Kong*. Optical lateral flow test strip biosensors for pesticides: Recent advances and future trends. Trends in Analytical Chemistry, 2021, 144: 116427.
3. Mingxuan Jia, Xiaofang Liao, Ling Fang, Boyu Jia, Miao Liu, Donghui Li, Lidong Zhou, Weijun Kong*. Recent advances on immunosensors for mycotoxins in foods and other commodities. Trends in Analytical Chemistry, 2021, 136: 116193.
4. Boyu Jia, Xiaofang Liao, Chaonan Sun, Ling Fang, Lidong Zhou*, Weijun Kong*. Development of a quantum dot nanobead-based fluorescent strip immunosensor for on-site detection of aflatoxin B1 in lotus seeds. Food Chemistry, 2021, 356: 129614.
5. Xiaofei Liu, Xiaofang Liao, Boyu Jia, Chaonan Sun, Lidong Zhou, Weijun Kong*. Development of a multi-channel magnetic bead micro-probe assay for high-throughput detection of zearalenone in edible and medicinal Coix seed. Food Chemistry, 2021, 347: 128977.
6. Ling Fang, Xiaofang Liao, Qing Zhang, Linchun Shi, Lidong Zhou, Haiping Zhao*, Weijun Kong*. An orthogonal experimental design and QuEChERS based UFLC-MS/MS for multi-pesticides and human exposure risk assessment in Honeysuckle. Industrial Crops & Products, 2021, 164: 113384.
7. Nan Long#, Jinxin Liu#, Xiaofang Liao, Boyu Jia, Jiali Liu, Lidong Zhou, Linchun Shi*, Weijun Kong*. Fungal communities in Nelumbinis semen characterized by high-throughput sequencing. International Journal of Food Microbiology, 2021, 359: 109428.
8. Qiutao Liu, Lingling Jiang, Lihe Xiao, Weijun Kong*. Physico?chemical characteristics and aflatoxins production of Atractylodis Rhizoma to different storage temperatures and humidities. AMB Express, 2021, 11: 155.
9. Yujiao Hou, Boyu Jia, Xiaofang Liao, Lizhu Fu, Xin Zhang, Lidong Zhou, Weijun Kong*. Nanozyme-based biosensors for exogenous contaminant detection in foods. Mini-Reviews in Organic Chemistry, 2021, 18: 1049-1063.
2020年：
1. Ling Fang, Xiaofang Liao, Boyu Jia, Linchun Shi, Linzhi Kang, Lidong Zhou*, Weijun Kong*. Recent progress in immunosensors for pesticides. Biosensors and Bioelectronics, 2020, 164: 112255.
2. Chaonan Sun, Xiaofang Liao, Pinxuan Huang, Guangzhi Shan, Xiao Ma, Lizhu Fu, Lidong Zhou?, Weijun Kong*. A self-assembled electrochemical immunosensor for ultra-sensitive detection of ochratoxin A in medicinal and edible malt. Food Chemistry, 2020, 315: 126289.
3. Chaonan Sun, Xiaofang Liao, Boyu Jia, Linchun Shi, Dingkun Zhang, Ruilin Wang, Lidong Zhou?, Weijun Kong*. Development of a ZnCdS@ZnS quantum dots-based label-free electrochemiluminescence immunosensor for sensitive determination of aflatoxin B1 in lotus seed. Microchimica Acta, 2020, 187: 236.
4. Xiaofang Liao, Boyu Jia, Chaonan Sun, Linchun Shi, Xi Liu, Lidong Zhou?, Weijun Kong*. Reuse of regenerated immunoaffinity column for excellent clean-up and low-cost detection of trace aflatoxins in malt. Microchemical Journal, 2020, 157, 105007.
5. Xiaofang Liao, Chaonan Sun, Fang Wei, Lidong Zhou*, Weijun Kong*. Exploration of the safe water content and activity control points for medicinal and edible lotus seeds from mildew. AMB Express, 2020, 10: 89.
2019年：
1. Xiaofei Liu, Guangyao Ying, Xiaofang Liao, Chaonan Sun, Fang Wei, Xiaoyan Xing, Linchun Shi, Yifan Sun, Weijun Kong*, Lidong Zhou*. Cytometric microbead magnetic suspension array for high-throughput ultrasensitive detection of aflatoxin B1. Analytical Chemistry, 2019, 91: 1194-1202.
2. Qiutao Liu, Changbin Xiao, Hongmei Liu, Yichen Hu, Weiying Guo, Weijun Kong*. Sensitive assessment of multi-class mycotoxins residue in Atractylodis rhizoma. Industrial Crops & Products, 2019, 127: 1-10.
3. Weijun Kong, Huijing An, Ji Zhang, Lan Sun, Yao Nan, Aili Song, Lidong Zhou. Development of a high-performance liquid chromatography with tandem mass spectrometry method for identifying common adulterant content in saffron (Crocus sativus L.). Journal of Pharmacy and Pharmacology, 2019, 71, 1864-1870.
4. Fang Wei, Xiaofei Liu, Xiaofang Liao, Linchun Shi, Shuwei Zhang, Jinghua Lu*, Lidong Zhou*, Weijun Kong*. Simultaneous determination of 19 mycotoxins in lotus seed using a multimycotoxin UFLC-MS/MS method. Journal of Pharmacy and Pharmacology, 2019, 71: 1172-1183.
5. Pinxuan Huang, Qiutao Liu, Jiabo Wang, Zhijie Ma, Jinghua Lu*, Weijun Kong?. Development of an economic ultrafast liquid chromatography with tandem mass spectrometry method for trace analysis of multiclass mycotoxins in Polygonum multiflorum. Journal of Separation Science, 2019, 42: 491-500.
2018年：
1. Xiaofei Liu, Guangyao Ying, Chaonan Sun, Meihua Yang, Lei Zhang, Shanshan Zhang, Xiaoyan Xing, Qian Li, Weijun Kong*. Development of an ultrasonication-assisted extraction based HPLC with a fluorescence method for sensitive determination of aflatoxins in highly acidic Hibiscus sabdariffa. Frontiers in Pharmacology, 2018, 9: 284.
2. Guangyao Ying, Xiaofei Liu, Haiwei Wang, Ruilin Wang, Xinping Ma, Weiying Guo, Weijun Kong*. An economic and green strategy for preventing Chinese medicinal materials from toxigenic fungi: Couplet medicine technique. Industrial Crops & Products, 2018, 124: 429-434.
3. Haiwei Wang, Zhixin Yang, Guangyao Ying, Meihua Yang, Yujiao Nian, Fang Wei, Weijun Kong*. Antifungal evaluation of plant essential oils and their major components against toxigenic fungi. Industrial Crops & Products, 2018, 120: 180-186.
4. Xi Liu, Xiaofei Liu, Pinxuan Huang, Fang Wei, Guangyao Ying, Jinghua Lu*, Lidong Zhou, Weijun Kong*. Regeneration and reuse of immunoaffinity column for highly efficient clean-up and economic detection of ochratoxin A in malt and ginger. Toxins, 2018, 10: 462.
5. Yujiao Nian, Haiwei Wang, Guangyao Ying, Meihua Yang, Ze Wang, Weijun Kong*, Shihai Yang*. Transfer rates of aflatoxins from herbal medicines to decoctions determined by an optimized high-performance liquid chromatography with fluorescence detection method. Journal of Pharmacy and Pharmacology, 2018, 70: 278-288.
3、發(fā)表著作
1）《水蛭的現(xiàn)代研究》，2020年，主編。
2）《中藥真菌及真菌毒素污染研究與對策》，2020年，編委。
3）《中藥質(zhì)量控制與分析》，2020年，編委。
4）《中藥質(zhì)量生物評價》，2018年，編委。