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臨床中藥方向

周勤梅

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一、個人簡介

周勤梅,博士學(xué)歷、高級實驗師、碩士生導(dǎo)師、成都中醫(yī)藥大學(xué)藥學(xué)院。主要從事中藥藥性理論和藥效物質(zhì)基礎(chǔ)研究。主持國家自然科學(xué)基金(廣藿香芳香倍半萜治療濕濁帶下霉菌性陰道炎的藥效物質(zhì)與作用機制)、四川省自然科學(xué)基金(基于Ca2+/CaMK/CREB/BDNF信號通路研究芳香化濕藥廣藿香醒脾解郁的效應(yīng)物質(zhì)和作用機制)等各級項目5項;主研國家自然基金重點項目、國家自然基金面上項目、四川省杰出青年基金等項目。共發(fā)表學(xué)術(shù)論文40余篇,其中,以第一作者或通訊作者發(fā)表SCI論文8篇、北大中文核心期刊論文10余篇,出版著作1部,獲得授權(quán)發(fā)明專利7項。

二、代表性成果(可含承擔(dān)項目、發(fā)表論文、論著、獲獎等)

發(fā)表論文(#為第一作者,*為通訊作者)

1. Qin-Mei Zhou#, Hao-Yu Zhao#, Chuan Ma#, Lu Huang, Jie Liu, Li Guo, Cheng Peng*, Liang Xiong*. Pocahemiketone A, a sesquiterpenoid possessing a spirocyclic skeleton with a hemiketal endoperoxide unit, alleviates Aβ25-35-induced proptosis and oxidative stress in SH-SY5Y cells[J]. Organic Letters, 2022, 24, 4734-4738.

2. Lu Huang, Cheng Peng*, Li Guo, Rui Feng, Hong-Zhen Shu, Yun-Cai Tian, Qin-Mei Zhou*, Liang Xiong*. Six pairs of enantiomeric phthalide dimers from the rhizomes of Ligusticum chuanxiong and their absolute configurations and anti-inflammatory activities[J]. Bioorganic Chemistry, 2022, 127: 105970.

3. Jing Zuo#, Tian-Hao Zhang#, Liang Xiong, Lu Huang, Cheng Peng, Qin-Mei Zhou*, Ou Dai*. Two pairs of 7,7′-cyclolignan enantiomers with anti-inflammatory activities from Perilla frutescens[J]. Molecules, 2022, 27: 6102.

4. Hao‐Yu Zhao#, Qin‐Mei Zhou#, Huan Zhu, Fei Zhou, Chun‐Wang Meng, Hong‐Zhen Shu, Zhao‐Hua Liu, Cheng Peng*, Liang Xiong*. Anisotanols A–D, four norsesquiterpenoids with an unprecedented sesquiterpenoid skeleton from Anisodus tanguticus[J]. Chinese Journal of Chemistry, 2021, 39: 3375-3380

5. Fei Zhou#, Ou Dai#, Cheng Peng*, Liang Xiong, Hui Ao, Fei Liu, Qin-Mei Zhou*. Pro-angiogenic effects of essential oil from Perilla frutescens and its main component (Perillaldehyde) on zebrafsh embryos and human umbilical vein endothelial cells[J]. Drug Design, Development and Therapy, 2021, 15: 4985-4999.

6. Xiao-Ya Wang#, Qin-Mei Zhou#, Li Guo, Ou Dai, Chun-Wang Meng, Lu-Lin Miao, Jie Liu, Qiao Lin, Cheng Peng*, Liang Xiong*. Cardioprotective effects and concentration-response relationship of aminoalcohol-diterpenoid alkaloids from Aconitum carmichaelii[J]. Fitoterapia, 2021, 149: 104822.

7. Qin-Mei Zhou#, Ming-Hua Chen#, Xiao-Hong Li, Cheng Peng*, Da-Sheng Lin, Xiao-Nian Li, Yang He, Liang Xiong*. Absolute Configurations and Bioactivities of Guaiane-Type Sesquiterpenoids Isolated from Pogostemon cablin[J]. Journal of Natural Products, 2018, 81(9): 1919-1927.

8. Huan Zhu#, Qin-Mei Zhou#, Cheng Peng*, Ming-Hua Chen, Xiao-Nian Li, Da-Sheng Lin, Liang Xiong*. Pocahemiketals A and B, two new hemiketals with unprecedented sesquiterpenoid skeletons from Pogostemon cablin[J]. Fitoterapia, 2017, 120: 67-71.


終審:藥學(xué)院總管理賬號
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