郭力
個(gè)人簡(jiǎn)介
郭力，博士，教授，博士生導(dǎo)師，藥學(xué)院；國(guó)務(wù)院政府津貼獲得者，四川省學(xué)術(shù)和技術(shù)帶頭人，四川省中醫(yī)藥學(xué)術(shù)和技術(shù)帶頭人，四川省有突出貢獻(xiàn)優(yōu)秀專家，國(guó)家自然基金生命科學(xué)部函審專家，四川省食藥監(jiān)局藥品審評(píng)專家；長(zhǎng)期從事中藥化學(xué)成分與質(zhì)量標(biāo)準(zhǔn)化研究，探索和闡明中藥藥效物質(zhì)基礎(chǔ)，重點(diǎn)圍繞川產(chǎn)道地藥材附子、石斛、川芎等品種的化學(xué)成分、炮制、配伍等多方面展開研究，對(duì)建立其質(zhì)量控制體系進(jìn)行了積極探索。近五年來(lái)主持主研科研項(xiàng)目10余項(xiàng)，主持及參與國(guó)家自然科學(xué)基金項(xiàng)目2項(xiàng)，國(guó)家科技部項(xiàng)目1項(xiàng)，四川省創(chuàng)新團(tuán)隊(duì)項(xiàng)目2項(xiàng)，四川省科技廳項(xiàng)目2項(xiàng)；發(fā)表論文80余篇(SCI收錄20余篇)，出版專著20余部；申請(qǐng)專利30項(xiàng)（授權(quán)14項(xiàng)）；獲國(guó)家科技進(jìn)步二等獎(jiǎng)1次，獲省科技進(jìn)步一等獎(jiǎng)3次；培養(yǎng)博士、碩士研究生50余人。
代表性成果
成都中醫(yī)藥大學(xué)，中藥學(xué)學(xué)科特色創(chuàng)新科研團(tuán)隊(duì)，CXTD2018012，川產(chǎn)道地藥材綜合研究與應(yīng)用開發(fā)創(chuàng)新團(tuán)隊(duì)，2018-06至2020-06，100萬(wàn)元，在研，主持
國(guó)家科技部，國(guó)家重點(diǎn)研發(fā)項(xiàng)目，2017YFC1701804，高品質(zhì)道地藥材中藥材附子規(guī)?；N植及精準(zhǔn)扶貧示范研究，2018-01至2021-12，425萬(wàn)元，在研，主研
四川省科技廳，四川省科技基礎(chǔ)條件平臺(tái)項(xiàng)目，2019JDPT0032，四川省中藥化合物資源共享平臺(tái)，2019-01至2021-12,30萬(wàn)元，在研，主研
國(guó)家自然科學(xué)基金，區(qū)域創(chuàng)新發(fā)展聯(lián)合基金，U19A2010，川產(chǎn)道地藥材的道地性研究，2020-01至2023-12，247萬(wàn)元，在研，主研
Xiao Haijun#; Guo Yiping#; Liu Hongmei; Liu Yushi; Wang Yumin; Li Changqing; Jaroslav Císa?; David ?koda; Ivo Ku?itka; Guo Li*; Vladimír Sedlar?íkp*; Structure-based design of charge-conversional drug self-delivery systems for better targeted cancer therapy, Biomaterials, 2020, 232.
Li He#; Qian Su#; Lan Bai#; Meifeng Li; Juanru Liu; Xiaomei Liu; Cunyan Zhang; Zhongliang Jiang; Jun He; Jianyou Shi*; Shan Huang*; Li Guo*; Recent research progress on natural small molecule bibenzyls and its derivatives in Dendrobium species, European Journal of Medicinal Chemistry, 2020, 112530.
Zhang Zhen##; Jiang Maoyuan#; Wei Xinyi; Shi Jingfeng; Geng Zhao; Yang Shasah; Fu Chaomei*; Guo Li*; Rapid discovery of chemical constituents and absorbed components in rat serum after oral administration of Fuzi-Lizhong pill based on high-throughput HPLC-Q-TOF/MS analysis, Chinese Medcine, 2019, 14(6): 1-22.
Liu Hongmei; Fang Chengxin; Zhang Tingmo; Guo Li*; Ye Qiang*; Molecular authentication and differentiation of Dendrobium species by rDNA ITS region sequence analysis, AMB Express, 2019, 9(53): 1-9
Ye Qiang; Liu Hongmei; Fang Chengxin; Liu Yushi; Liu Xiaomei; Liu Juanru; Zhang Cunyan; Zhang Tingmo; Peng Cheng*; Guo Li*; Cardiotoxicity evaluation and comparison of diterpene alkaloids on zebrafish, Drug and Chemical Toxicology, 2019: 1-8.
Zhang Xiao; Zou, Lihua; He Yulin; Peng Cheng; Guo Li*; Xiong Liang*. Triterpenoid saponins from the buds of Lonicera similis. Natural Product Research, 2018, 32: 2282-2290.