嚴(yán)鑄云
個(gè)人簡介
嚴(yán)鑄云，博士、教授，碩士和博士研究生導(dǎo)師；四川省學(xué)術(shù)和技術(shù)帶頭人，四川省中醫(yī)藥管理局學(xué)術(shù)和技術(shù)帶頭人，第四批全國老中醫(yī)藥專家學(xué)術(shù)經(jīng)驗(yàn)繼承人；兼任全國藥用植物學(xué)課程聯(lián)盟副理事長，中國植物學(xué)會(huì)藥用植物與植物藥專業(yè)委員會(huì)委員，全國中藥種子（苗）標(biāo)準(zhǔn)化委員會(huì)委員，中國生態(tài)學(xué)會(huì)中藥資源生態(tài)專業(yè)委員會(huì)委員，四川省藥學(xué)會(huì)中藥與天然藥專業(yè)委員會(huì)委員，中國自然資源學(xué)會(huì)天然藥物資源專業(yè)委員會(huì)委員，中國植物學(xué)會(huì)四川分會(huì)理事、副秘書長；
研究方向
道地藥材品質(zhì)形成與調(diào)控機(jī)制研究、中藥資源品質(zhì)評(píng)價(jià)研究；先后主持國家支撐計(jì)劃、國家重點(diǎn)研發(fā)計(jì)劃和國家自然科學(xué)基金等課題20余項(xiàng)；倡導(dǎo)基于中藥性效的品質(zhì)控制和資源開發(fā)策略，提出中藥物質(zhì)基礎(chǔ)是植物與內(nèi)生菌共代謝的產(chǎn)物，連作障礙是土壤微生態(tài)失衡應(yīng)終結(jié)于生態(tài)平衡的研究思想，開啟了中藥微生態(tài)研究的新領(lǐng)域；圍繞丹參、川芎、川貝母等的品質(zhì)形成機(jī)制和微生態(tài)調(diào)控開展研究工作；在International Journal of Biological Macromolecules、Food Science and Technology、Frontiers in plant science、中國中藥雜志等期刊發(fā)表論文200余篇，獲省部級(jí)科學(xué)技術(shù)進(jìn)步二等獎(jiǎng)1項(xiàng)、三等獎(jiǎng)3項(xiàng)，省級(jí)教學(xué)成果一等獎(jiǎng)2項(xiàng)、二等獎(jiǎng)1項(xiàng)，授權(quán)專利3項(xiàng)；出版專著和教材20余部，其中主編國家級(jí)規(guī)劃教材《藥用植物學(xué)》、《中藥拉丁語》、《四省藏區(qū)中藥材生產(chǎn)加工適宜技術(shù)》、《中藥微生態(tài)學(xué)》等10部，副主編《中藥資源專論》（研究生教材）、《中國藥用植物志》、《中國民族藥辭典》等9部。
代表性成果
[1] Yu Liu, Ke Wang, Zhuyun Yan, Xiaofeng Shen, Xinjie Yang. Prediction of active ingredients in Salvia miltiorrhiza Bunge. based on soil elements and artificial neural network[J].PeerJ, 2022: e12726
[2] Ke Wang, Zhuyun Yan, Yuntong Ma, Bo Li, Wei Wang, Luming Qi, Hongmei Jia, Na Li, Zhun Wang. A Mathematical Model for Characterizing the Biomass and the Physiological/Biochemical Indicators of Salvia miltiorrhiza Based on Growth-Defense Tradeoff[J].Frontiers in plant science,2022: e793574
[3] Yu Liu, Maoling Tan, Wenjing Zhu, Yanan Cao, Lianxin Peng, Zhuyun Yan, Gang Zhao.In Vitro Effects of Tartary Buckwheat-Derived Nanovesicles on Gut Microbiota[J]. Journal of agricultural and food chemistry, 2022: 2616-2629
[4] Hongyang Lv, Xiaorui Zhang, Yuanyuan Ren, Yijia Zeng, Qian Fang, Qinwen Fu, Dongmei He, Zhuyun Yan. Title The Use of GC‐MS and Network Pharmacology to Analyze the Material Basis and Mechanism of Ligusticum chuanxiong Hort. in Treating Chronic Cerebral Circulation Insufficiency[J].Chemistry Select,2022:1-13
[5] Zhendong Yao, Yanan Cao, Lianxin Peng, Zhuyun Yan, Gang Zhao. Coarse Cereals and Legume Grains Exert Beneficial Effects through Their Interaction with Gut Microbiota: A Review[J]. Journal of agricultural and food chemistry, 2021:861-877
[6] Jingwen Zhou, Rui Liu, Min Shuai, Zhuyun Yan, Xin Chen. Comparative transcriptome analyses of different Salvia miltiorrhiza varieties during the accumulation of tanshinones [J].Peer J,2021:e12300
[7] Bujin Ma, Jing Ma, Bo Li, Qian Tao, Jiaxia Gan, Zhuyun Yan. Effects of different harvesting times and processing methods on the quality of cultivated Fritillaria cirrhosa D. Don[J].Food science & nutrition, 2021,6:2853-2861
[8] Yanhong Wu, Hai Wang, Min Liu, Bo Li, Xin Chen,Yuntong Ma, Zhuyun Yan. Effects of Native Arbuscular Mycorrhizae Isolated on Root Biomass and Secondary Metabolites of Salvia miltiorrhiza Bge.[J]. Frontiers in plant science,2021:617892
[9] Lei Kang, Dongmei He, Hai Wang, Guiqi Han, Hongyang Lv, Wanting Xiao, Zhanling Zhang, Zhuyun Yan, Luqi Huang. “Breeding on Mountains" Resulted in the Reorganization of Endophytic Fungi in Asexually Propagated Plants (Ligusticum chuanxiong Hort.)[J].Frontiers in plant science, 2021:740456
[10] Yurui Wu, Cuibai Li, Yanhong Wu, Lan Li, Wenbo Li, Bujin Ma, Zhuyun Yan. Diversity and function of culturable actinobacteria in the root-associated of Salvia miltiorrhiza Bunge[J].Peer J,2021:e11749
[11] Wenjing Zhu, Yu Liu, Yanan Cao, Lianxin Peng, Zhuyun Yan, Gang Zhao. Insights into Health-Promoting Effects of Plant MicroRNAs: A Review[J].Journal of agricultural and food chemistry,2021:4372–14386
[12] Baojie Zhu, Zhuyun Yan, Liang Hong, Shaoping Li, Jing Zhao. Quality evaluation of Salvia miltiorrhiza from different geographical origins in China based on qualitative and quantitative saccharide mapping and chemometrics[J].Journal of pharmaceutical and biomedical analysis,2020:113583
[13] Furong Zhong, Ling Huang, Luming Qi, Yuntong Ma, zhuyun Yan. Full-length Transcriptome Analysis of Coptis Deltoidea and Identification of Putative Genes Involved in Benzylisoquinoline Alkaloids Biosynthesis Based on Combined Sequencing Platforms[J].Plant molecular biology,2020: 4/5:477-499
[14] Yanhong Wu, Yurui Wu, Bo Li, Zhuyun Yan. Cryptotanshinone: A review of its pharmacology activities and molecular mechanisms[J]. Fitoterapia,2020:104633
[15] Luming Qi, Furong Zhong, Yang Chen, Shengnan Mao, Zhuyun Yan, Yuntong Ma. An integrated spectroscopic strategy to trace the geographical origins of emblic medicines: Application for the quality assessment of natural medicines[J].Journal of Pharmaceutical Analysis,2020,(4):356-364
[16] Ting Chen, Furong Zhong, Cheng Yao, Jia Chen, Yiqing Xiang, Jijing Dong, Zhuyun Yan, Yuntong Ma. A Systematic Review on Traditional Uses, Sources, Phytochemistry, Pharmacology, Pharmacokinetics, and Toxicity of Fritillariae Cirrhosae Bulbus[J].Evidence-based complementary and alternative medicine : eCAM, 2020:1536534
[17] Lianxin Peng, Qu Zhang, Yanhong Zhang, Zhendong Yao, Panpan Song, Lijuan Wei, Gang Zhao, Zhuyun Yan. Effect of tartary buckwheat, rutin, and quercetin on lipid metabolism in rats during high dietary fat intake[J].Food Science & Nutrition,2020,(1):199-213
[18] Kui Zhao, Bo Li, Dongmei He, Can Zhao, Zhengjun Shi, Binbin Dong, Duo Pan, Rahul Rangrao Patil, Zhuyun Yan, Zhanhu Guo. Chemical characteristic and bioactivity of hemicellulose-based polysaccharides isolated from Salvia miltiorrhiza[J]. International Journal of Biological Macromolecules, 2020, Part B: 2475-2483
[19] 嚴(yán)鑄云,何冬梅,王海,展望微生態(tài)理論和技術(shù)在中藥研究中的應(yīng)用[J].中藥與臨床,2017,8(5):18-22.
[20] 嚴(yán)鑄云,略論中藥資源科學(xué)面臨的現(xiàn)實(shí)與挑戰(zhàn)[J].中藥與臨床,2012,0(6):1-5.