裴瑾
一、個人簡介
裴瑾，博士，教授，博士生導(dǎo)師。西南特色中藥資源國家重點(diǎn)實(shí)驗(yàn)室常務(wù)副主任，藥學(xué)院/現(xiàn)代中藥產(chǎn)業(yè)學(xué)院副院長。
國家中藥種質(zhì)資源庫技術(shù)負(fù)責(zé)人，中藥材標(biāo)準(zhǔn)化教育部重點(diǎn)實(shí)驗(yàn)室副主任。中華中醫(yī)藥學(xué)會中藥鑒定專業(yè)委員會副會長，世界中醫(yī)藥學(xué)會聯(lián)合會道地藥材多維評價專業(yè)委員會秘書長，中國食品藥品企業(yè)質(zhì)量安全促進(jìn)會區(qū)塊鏈委員會副主任委員。四川省學(xué)術(shù)和技術(shù)帶頭人，四川省中醫(yī)藥學(xué)術(shù)和技術(shù)帶頭人，四川省中醫(yī)藥重點(diǎn)學(xué)科——藥用植物學(xué)帶頭人，國家一流本科專業(yè)“中藥資源與開發(fā)”負(fù)責(zé)人，規(guī)劃教材《中藥資源學(xué)》主編。
圍繞中藥資源可持續(xù)發(fā)展重大戰(zhàn)略需求，從事中藥資源保存與質(zhì)量提升、道地藥材品質(zhì)形成機(jī)制和調(diào)控研究。構(gòu)建我國中藥種質(zhì)低溫保存技術(shù)體系，主持國家財政部、國家中醫(yī)藥管理局專項(xiàng)“中藥種質(zhì)資源庫”、中藥資源保障能力提升項(xiàng)目“中藥資源戰(zhàn)略性收集保存與保護(hù)”及四川省科技支撐計劃“中藥種質(zhì)資源庫建設(shè)關(guān)鍵技術(shù)研究及示范”等；主持“全國第四次中藥資源普查四川2017-2019內(nèi)業(yè)整理”，鑒定四川省46個縣蠟葉標(biāo)本13萬份、藥材3500余份、種苗2200余份；構(gòu)建基于中藥品質(zhì)形成分子機(jī)制的“中藥品質(zhì)育種”研究策略，圍繞紅花、川牛膝、白芷等川產(chǎn)道地藥材品質(zhì)形成及新品種培育開展系統(tǒng)研究，主持國家自然科學(xué)基金“基于響應(yīng)環(huán)境-調(diào)控合成功能基因解析紅花有效成分積累的分子機(jī)制”“基于‘靶態(tài)’表型組與Stacking集成學(xué)習(xí)解析番紅花 ‘葉-種球’表里關(guān)系構(gòu)建種球質(zhì)量預(yù)測模型”、四川省“十四五”育種攻關(guān)“突破性道地中藥材育種材料和方法創(chuàng)新及新品種選育——紅花”等，挖掘中藥品質(zhì)特性功能基因、開展中藥新品種選育，并指導(dǎo)生產(chǎn)；致力于中藥標(biāo)準(zhǔn)化研究，主持/參與ISO中醫(yī)藥國際標(biāo)準(zhǔn)“中藥-西紅花”“中藥-紅花”的制定及“泰國常用中藥質(zhì)量標(biāo)準(zhǔn)化”項(xiàng)目等。
在Industrial Crops & Products、Phytomedicine、BMC Plant Biology、藥學(xué)學(xué)報、中國中藥雜志等發(fā)表論文兩百余篇，包括一區(qū)TOP、高被引論文；副主編“十二五”“十三五”國家重大出版工程項(xiàng)目《中國藥用植物志》（第三卷）、《中國臨床藥物大辭典》（飲片卷、中藥成方制劑卷），《新編中國藥材學(xué)》（第七卷），2021年獲中國政府出版獎。
二、代表性成果
1、Tao Zhou, Xue Qiu, Li Zhao, Weijing Yang, Feiyan Wen, Qinghua Wu, Jie Yan, Binjie Xu, Jiang Chen, Yuntong Ma*, Jin Pei*.Optimal light intensity and quality increased the saffron daughter corm yield by inhibiting the degradation of reserves in mother corms during the reproductive stage[J]. Industrial Crops&Products, 2022,Volume176.(Q1,top)
2、Tiexin Zeng, Xiao Sun, Yujing Miao, ShengjiuGu, Lixia Tian, Yan Zheng, Yuan Jiang, XinkeZhang, Zhan Feng, Jin Pei*, Linfang Huang *.Integrating bioclimatic factors and secondary metabolism to predict the suitable producing area of plants with high specific metabolite content in a real-world environment - a case of Carthamus tinctorius L.[J]. Industrial Crops&Products, 2022,Volume177.(Q1,top)
3、Bin Xian, Rui Wang, Huajuan Jiang, Yongfeng Zhou, Jie Yan, Xulong Huang, Jiang Chen, Qinghua Wu, Chao Chen, Ziqing Xi, Chaoxiang Ren*, Jin Pei*. Comprehensive review of two groups of flavonoids in Carthamus tinctorius L.[J]. Biomed Pharmacother. 2022 Sep; 153:113462. (Q1)
4、Lanyu Zhou, Lijie Lu, Chao Chen, Tao Zhou, Qinghua Wu, Feiyan Wen, Jiang Chen, Hugh W.Pritchard, Cheng Peng, Jin Pei*and Jie Yan*. Comparative changes in sugars and lipids show evidence of a critical node for regeneration in safflower seeds during aging.[J]. Front. Plant Sci. 2022.13.(Q1,top)
5、Xu-Long Huang, Hua-Juan Jiang, Jin Pei*, Qing-Hua Wu*, Wei-Hua Wu*, Chao-Xiang Ren, Lan-Yu Zhou, Yong-Feng Zhou, Bin Xian, Chao Chen, Yan-Hang Yan, Li-Jie Lu, Yue Wang, Xing-Long Zhu. Study on the potential mechanism, therapeutic drugs and prescriptions of insomnia based on bioinformatics and molecular docking.[J]. Comput Biol Med., 2022 Aug; 106001. (Q1)
6、Xiaominting Song, Huanan Rao, Chuanjie Guo, Bo Yang, Yali Ren, Miao Wang, Yuzhi Li, Zhixing Cao*, Jin Pei*. Myricetin exhibit selective anti-lymphoma activity by targeting BTK and is effective via oral administration in vivo[J]. Phytomedicine, 2021 Dec; 93:153802.(Q2,top)
7、Song X, Tan L, Wang M, Ren C, Guo C, YangB, Ren Y, Cao Z, Li Y*, Pei J*. Myricetin: A review of the most recent research[J]. Biomedicine & Pharmacotherapy, 2021 Feb; 134:111017.(Q2,top,高被引)
8、Shengju Wang, Huajuan Jiang, Qianqian Liu, Yongfeng Zhou, Yanfen Cheng, Tao Zhou, Jinming Zhang, Yao He, Chaoxiang Ren*, JinPei*. A comparative study on the traditional versus modern yellow rice wine processing methods using Taohong Siwu Decoction for pharmaceutical productio[J]. J Ethnopharmacol. 2022 May 23; 290:115114.(Q2)
9、Zhou Y, Niu M, Zhang D, Liu Z, Wu Q, Chen J, Zhang H, Zhang P*, Pei J*. Screening for Anti-Inflammation Quality Markers of Lianhua Qingwen Capsule Based on Network Pharmacology, UPLC, and Biological Activity[J]. Frontiers in Pharmacology, 2021 Jun 11; 12:648439.(Q2)
10、Chen J, Wang J, Wang R, Xian B, Ren C, Liu Q, Wu Q, Pei J*. Integrated metabolomics and transcriptome analysis on flavonoid biosynthesis in safflower (Carthamus tinctorius L.) under MeJA treatment[J]. BMC Plant Biol. 2020 Jul 29; 20(1):353.(Q2)
11、Chen J, Tang X, Ren C, Wei B, Wu Y, Wu Q, Pei J*. Full-length transcriptome sequences and the identification of putative genes for flavonoid biosynthesis in safflower[J]. BMC Genomics. 2018 Jul 24; 19(1):548.(Q2)
12、中藥大品種康復(fù)新液系統(tǒng)創(chuàng)新及產(chǎn)業(yè)化關(guān)鍵技術(shù)研究應(yīng)用，四川省科學(xué)技術(shù)進(jìn)步一等獎，2016
13、中藥品質(zhì)理論創(chuàng)建與實(shí)踐，四川省科學(xué)技術(shù)進(jìn)步二等獎，2012
14、遠(yuǎn)志飲片炮制工藝及質(zhì)量標(biāo)準(zhǔn)規(guī)范化研究，四川省科學(xué)技術(shù)進(jìn)步二等獎，2008
15、活血溫里復(fù)方中溫里藥提高活血藥生物利用度的研究，四川省科學(xué)技術(shù)進(jìn)步三等獎，2006