石三軍
一、個人簡介
?石三軍，教授、博士生導(dǎo)師。哈佛大學(xué)留學(xué)歸國，四川省中醫(yī)藥管理局學(xué)術(shù)和技術(shù)帶頭人和四川省學(xué)術(shù)和技術(shù)帶頭人后備人選、省部級優(yōu)秀人才計(jì)劃入選者、四川省特聘專家、四川省杰青、省級創(chuàng)新創(chuàng)業(yè)優(yōu)秀指導(dǎo)教師等；致力于傳統(tǒng)脂質(zhì)材料、新型安全材料在核酸蛋白藥物及中藥活性分子遞釋上的應(yīng)用基礎(chǔ)研究，其中開發(fā)的超分子復(fù)合物技術(shù)包載核酸藥物被多位美韓科學(xué)家評價(jià)為首次研究報(bào)道。相關(guān)成果以第一或通訊作者身份在Angew Chem Int Edit, Nano Today, J Control Release, Acta Pharmaceutica Sinica B等頂級雜志上發(fā)表SCI論文多篇，最高影響因子19，參編《藥劑學(xué)》和英文專著各1項(xiàng)，授權(quán)專利1項(xiàng)；先后主持了國家科技重大專項(xiàng)（726萬）、國家自然科學(xué)基金等項(xiàng)目8項(xiàng)，累計(jì)經(jīng)費(fèi)1000余萬元；成果先后獲得重慶市科技進(jìn)步二等獎、四川省科學(xué)技術(shù)進(jìn)步三等獎、重慶市科協(xié)自然科學(xué)優(yōu)秀學(xué)術(shù)論文，以及Int J Biol Macromol評審“杰出貢獻(xiàn)獎”等獎項(xiàng)；指導(dǎo)學(xué)生獲得“互聯(lián)網(wǎng)+”創(chuàng)新創(chuàng)業(yè)競賽國家級獎勵2項(xiàng)、“挑戰(zhàn)杯”大學(xué)生創(chuàng)業(yè)大賽國家級銅獎及“創(chuàng)青春”中國青年創(chuàng)新創(chuàng)業(yè)大賽銅獎，以及部省級創(chuàng)新創(chuàng)業(yè)獎勵10余項(xiàng)；同時(shí)擔(dān)任了本學(xué)科著名SCI期刊Curr Pharm Design客座主編、Evid Based Complement Alternat Med編委、Journal of Pharmaceutical Analysis (IF=14)青年編委、Frontiers in Pharmacology、Frontiers in Oncology客座編輯、SmartMat青年編委、《現(xiàn)代腫瘤醫(yī)學(xué)》編委，并任世中聯(lián)腫瘤精準(zhǔn)醫(yī)學(xué)專委會常務(wù)理事、中華中醫(yī)藥學(xué)會中成藥分會委員、省科青聯(lián)理事、省藥學(xué)會藥劑專委會委員等職務(wù)。
二、代表性成果
1.Dandan Mi, Jiaojiao Li, Rujing Wang, Yuke Li, Lan Zou, Chen Sun, Shenao Yan, Huan Yang, Mengnan Zhao*, Sanjun Shi*. Postsurgical wound management and prevention of triple-negative breast cancer recurrence with a pryoptosis-inducing, photopolymerizable hydrogel. Journal of Controlled Release, 2023. (IF=11.467)
2. Mengnan Zhao, Rujing Wang, Kunmeng Yang, Yuhong Jiang*, Yachen Peng, Yuke Li, Zhen Zhang, Jianxun Ding*, Sanjun Shi*. Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis. Acta Pharmaceutica Sinica B, 2022. (IF=14.9)
3. Yao Chen, Jiru Yang, Yi Zuo, Chaozheng Zhang, Yiru Pu, QingRen, XiaoLi, Yunqian Huang, Hui Huang, HuanYang, Ouyan You, Xila Xia, Aiping Lu, Sanjun Shi*, Yun Deng*, Jun Lu*. Voacamine is a novel inhibitor of EGFR exerting oncogenic activity against colorectal cancer through the mitochondrial pathway. Pharmacological Research, 2022; 184: 106415. (IF=10.334)
4. Yan Chen, Rui Zhang, Dandan Mi, Qiuju Wang, Tingwenli Huang, Xinwei Dong, Hongwei Zhang, Hongtao Xiao, Sanjun Shi*. SPK1/S1P axis confers gastrointestinal stromal tumors (GISTs) resistance of imatinib. Gastric Cancer, 2023; 26: 26-43. (IF=7.7)
5. Mengnan Zhao, Dandan Mi, Bijan Emiliano Ferdows, Yuke Li, Rujing Wang, Jiaojiao Li, Dylan Patel, Sanjun Shi*, Wei Tao*. State-of-the-art nanotechnologies for the detection, recovery, analysis and elimination of blood-based biosources in cancer liquid biopsy. Nano Today, 2022; 42: 101361. (IF=18.962)
6. Hanmei Li, Qi Tang, Yao Wang, Mao Li, Yannan Wang, Hong Zhu, Fang Geng, Di Wu, Lianxin Peng, Gang Zhao, Liang Zou, Sanjun Shi*. Injectable thermosensitive lipo-hydrogels loaded with ropivacaine for prolonging local anesthesia. International Journal of Pharmaceutics, 2021; 121291. (IF=6.5)
7. Hong Wang, Yu Zheng, Qiang Sun, Zhen Zhang, Mengnan Zhao, Cheng Peng*, Sanjun Shi*. Ginsenosides emerging as both bifunctional drugs and nanocarriers for enhanced antitumor therapies. Journal of Nanobiotechnology, 2021; 19: 322. (IF=9.43)
8. Sanjun Shi*, Wenliang Li. Cancer Stem Cell Based Targeted Therapy. Current Pharmaceutical Design, 2020; 26(17): 1951. (IF=3.3)
9. Xili Lu#, Sanjun Shi#, Hanmei Li, Ethan Gerhard, Zhihui Lu, Xinyu Tan, Wenliang Li, Kevin M.Rahn, Denghui Xie, Guodong Xu, Fang Zou, Xiaochun Bai, Jinshan Guo, Jian Yang. Magnesium oxide-crosslinked low-swelling citrate-based mussel-inspired tissue adhesives. Biomaterials, 2020; 232: 119719. (IF=15.3)
10. Lili Wei, Chenyuan Wang, Xianjue Chen, Bing Yang, Kun Shi, Leah R. Benington, Lee Yong Lim, Sanjun Shi*, Jingxin Mo*. Dual-responsive, methotrexate-loaded, ascorbic acid-derived micelles inhibit NF-κB signaling to exert anti-tumor and anti-metastasis effects in an orthotopic mouse model of human choriocarcinoma. Theranostics, 2019; 9(15): 4354-4374. (IF=11.6)
11. Sanjun Shi, Na Kong, Chan Feng, Aram Shajii, Claire Bejgrowicz, Wei Tao*, Omid C. Farokhzad*. Drug Delivery Strategies for the Treatment of Metabolic Diseases. Advanced Healthcare Materials, 2019, 1801655. (IF=11.1)
12. Yuanyuan Li#, Sanjun Shi#, Yue Ming, Linli Wang, Chenwen Li, Minghe Luo, Ziwei Li, Bin Li, Jianhong Chen. Specific cancer stem cell-therapy by albumin nanoparticles functionalized with CD44-mediated targeting. Journal of Nanobiotechnology, 2018; 16: 99. (IF=9.4)
13. Minghe Luo, Yue Ming, Linli Wang, Yuanyuan Li, Bin Li, Jianhong Chen, Sanjun Shi*. Local delivery of deep marine fungus-derived equisetin from polyvinylpyrrolidone (PVP) nanofibers for anti-MRSA activity. Chemical Engineering Journal, 2018; 350: 157-163. (IF=16.7)
14. Sanjun Shi, Likai Yang, Qiu’e Yao, Xin Li, Yue Ming, Yu Zhao. Ascorbic palmitate as a bifunctional drug and nanocarrier of paclitaxel for synergistic anti-tumor therapy. Journal of Biomedical Nanotechnology, 2018; 14: 1601-1612. (IF=3.64)
15. Sanjun Shi, Yuanyuan Li, Yue Ming, Chenwen Li, Ziwei Li, Jianhong Chen and Minghe Luo*. Biological activity and chemical composition of the endophytic fungus Fusarium sp. TP-G1 obtained from the root of Dendrobium officinale Kimura et Migo. Records of Natural Products, 2018; 12(6): 549-556. (IF=2)
16. Min Zhou, Xin Li, Yuanyuan Li, Qiu’e Yao, Yue Ming, Ziwei Li, Laichun Lu, Sanjun Shi*. Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy. Drug Delivery, 2017; 24: 1230-1242. (IF=6.82)
17. Hanmei Li, Tao Liu, Yuxuan Zhu, Qiang Fu, Wanxia Wu, Jie Deng, Li Lan, Sanjun Shi*. An in situ-forming phospholipid-based phase transition gel prolongs the duration of local anesthesia for ropivacaine with minimal toxicity. Acta Biomaterialia, 2017; 58, 136-145. (IF=10.63)
18. Sanjun Shi*, Min Zhou, Xin Li, et. al. Synergistic active targeting of dually integrin αvβ3/CD44-targeted nanoparticles to B16F10 tumors located at different sitxes of mouse bodies. J Control Release, 2016; 235: 1-13. (JCR1區(qū)，IF=11.47)
19. Sanjun Shi, Lu Han, Tao Gong, Zhirong Zhang, Xun Sun. Systemic delivery of microRNA-34a for cancer stem cell therapy. Angew Chem Int Edit, 2013; 52(14): 3901-3905. (IF=16.82)
20. Sanjun Shi, Lu Han, Li Deng, Yanling Zhang, Hongxin Shen, Tao Gong, Zhirong Zhang, Xun Sun. Dual drugs (microRNA-34a and paclitaxel)-loaded functional solid lipid nanoparticles for synergistic cancer cell suppression. J Control Release, 2014; 194(28): 228-237. (IF=11.47)
聯(lián)系方式：
成都中醫(yī)藥大學(xué)科技樓西耳房1樓
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