謝 欣
謝欣，醫(yī)學(xué)博士/博士后，高級實驗師，醫(yī)學(xué)技術(shù)學(xué)院教職工第一黨支部書記。主要研究方向為中藥藥效物質(zhì)的分子作用機制和多維構(gòu)效關(guān)系闡明、中藥活性成分的結(jié)構(gòu)修飾及中藥新藥發(fā)現(xiàn)。曾獲2019年四川省科技進步一等獎（第七完成人）。
先后主持國家博士后課題2項（面上項目1項及特別資助項目1項）、四川省科技廳項目1項、成都中醫(yī)藥大學(xué)“杏林學(xué)者”課題3項；參與國家自然基金5項。相關(guān)成果發(fā)表在Chemical Communications; Advanced Synthesis & Catalysis; Synletter；The Chemical Record 等知名期刊，共計SCI收錄15篇，其中以第一作者或通訊發(fā)表SCI論文10篇、其中IF大于5論文8篇，學(xué)科領(lǐng)域JCR一區(qū)論文3篇、ESI高被引論文1篇。獲得國家授權(quán)發(fā)明專利5項；參編專著5部。
※ 近年來主要代表性論文
[1] Xie, X.; Xiong, S.-S.; Li, X.; Huang, H.; Wu, F.-B.; Shen, P.-F.; Cheng Peng, He, G.*; Han, B.* Design and organocatalytic synthesis of spirooxindole–cyclopentene–isoxazole hybrids as novel MDM2–p53 inhibitors. Organic Chemistry Frontiers 2021,8, 1836-1843. IF 5.155
[2]Xie, X.; Xiang, L.; Peng, C.*; Han, B*. Catalytic Asymmetric Synthesis of Spiropyrazolones and their Application in Medicinal Chemistry. Chemical Record 2019, 19(11), 2209. IF: 6.163
[3]Xie, X.; Huang, W.; Peng, C.*; Han, B.* Organocatalytic Asymmetric Synthesis of Six-Membered Carbocycle-Based Spiro Compounds. Advanced Synthesis & Catalysis 2018, 360, 194-228. IF 5.646
[4] Xie, X.; Peng, C.*; He, G.; Leng, H.-J.; Wang, B.; Huang, W.*; Han, B.* Asymmetric synthesis of a structurally and stereochemically complex spirooxindole pyran scaffold through an organocatalytic multicomponent cascade reaction. Chemical Communications 2012, 48(85): 10487. IF: 5.996
[5]Xie, X.; Peng C. *; Leng H. J.; Wang B.; Tang Z. W.; Huang W*. Asymmetric synthesis of oxa-spirocyclic indanones with structural complexity via an organocatalytic Michael–Henry–Acetalization cascade. Synlett 2014, 25, 143-147. IF 2.419
[6]Mu, J.?; Xie, X.?; Xiong, S.-S.; Zhang, Y.-H.; Wang, Y.-T.; Zhao, Q.; Zhu H.-P.; Huang, W.*; He, G.* Discovery of spirooxindole–ferrocene hybrids as novel MDM2 inhibitors. Chinese Chemical Letters 2021, 32, 1897-1901. IF 4.632
[7]Han, B.?; Xie, X.?; Huang, W.; Li, X.; Yang, L.; Peng, C.* Organocatalytic Morita-Baylis-Hillman/Michael/Acetalization Cascade: Procedure-Controlled Diastereodivergence in the Asymmetric Synthesis of Fully Substituted Tetrahydropyrans. Advanced Synthesis & Catalysis 2014, 356(17), 3676. IF: 5.851
[8]Tang, Z. W.?; Xie, X.?; Huang, W.; Leng, H. J.; Wang, B.; Han, B.*; Peng, C.* Exploring the Antibacterial Target of the Main Constituent of Pogostemon cablin by using Molecular Docking and Network Analysis. Latin American Journal of Pharmacy 2016, 35, 502-509. IF 0.298
※ 近年來主出版專著
(1)中國臨床藥物大詞典. 中藥飲片卷. 中國醫(yī)藥科技出版社. 常務(wù)編委. 2018
(2)中國臨床藥物大詞典. 成方制劑卷. 中國醫(yī)藥科技出版社. 常務(wù)編委. 2018
(3)有毒中藥附子、川烏、草烏的安全性評價與應(yīng)用. 四川科學(xué)技術(shù)出版社. 編委. 2014
(4)中華道地藥材. 中國中醫(yī)藥出版社. 編委. 2013